Background: Polycystic Ovary Syndrome (PCOS) is one of the most common endocrine disorders affecting women of reproductive age. It is characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology. PCOS is associated with metabolic disturbances, infertility, cardiovascular risks, and psychological disorders.

Objective: This review evaluates current clinical management strategies for PCOS, focusing on diagnosis, lifestyle interventions, pharmacological therapies, fertility management, and emerging therapeutic approaches.

Methods: A comprehensive review of published literature from international databases was conducted. Evidence regarding diagnosis, treatment modalities, and long-term management was critically analyzed.

Results: Effective management requires individualized and multidisciplinary approaches. Lifestyle modification remains the cornerstone of treatment. Pharmacological interventions such as metformin, oral contraceptives, anti-androgens, and ovulation induction agents demonstrate significant benefits. Emerging therapies targeting insulin resistance and inflammation show promising outcomes.

Conclusion: Early diagnosis and personalized treatment improve reproductive, metabolic, and psychological outcomes in women with PCOS. Future research should focus on precision medicine approaches and novel therapeutic targets.